CRISPR To Lose Its CFO In September, Hunt For Successor Begins

As disclosed previously on a Current Report on Form 8-K filed with the Securities and Exchange Commission on March20, 2017, Marc Becker, Senior Vice President and Chief Financial Officer of CRISPR Therapeutics AG (the “Company”), took a family and medical leave of absence.Mr.Becker will not resume his duties as the Company’s principal financial officer or principal accounting officer. He will be transitioning his remaining responsibilities at the Company over the coming months and will be leaving his functions at the Company as of September30, 2017.

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