As Blockbuster Drugs Fizzle, Biotech Looks Warily To The Next Big Thing

Has the age of the biotech blockbuster come to a close?

Over the past year, a string of would-be best-sellers, expected to generate billions in sales, have wilted into commercial disappointments amid a fractious debate about the cost of medicine. Another highly touted — and highly priced — treatment won approval on Tuesday, and the industry may soon find out whether those failures were aberrant blips or a frightening glimpse of the new normal.

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